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Study: Mental confusion can be early symptom of Covid
"The main hypotheses which explain how the coronavirus affects the brain point to three possible causes: hypoxia or neuronal oxygen deficiency, inflammation of brain tissue due to cytokine storm and the fact that the virus has the ability to cross the blood-brain barrier to directly invade the brain," commented Correa. He stressed that any one of these three factors has the potential to result in delirium and explained that evidence of hypoxia-related brain damage.
It has been observed in autopsies carried out on patients who have died from the infection and that it has been possible to isolate the virus from the cerebral tissue. According to the researchers, delirium, cognitive deficits and behavioural anomalies are most likely to be the result of systemic inflammation of the organ and a state of hypoxia.
"It also causes the neuronal tissue to become inflamed and cause damage in areas such as the hippocampus, which are associated with the cognitive dysfunctions and behavioural alterations presented by patients suffering delirium," the team explained.
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